This new probiotic 101 answers to teach you all about probiotic health, it will also teach you about the microbiome 101.
“Probiotic strains have been studied extensively in clinical trials to support digestion and gastrointestinal function. For example, in a 300-person study, researchers discovered that two specific strains (Lactobacillus plantarum SD-LP1-IT and Bifidobacterium breve SD-BR3-IT) supported gastrointestinal functions in people with digestive issues.10 These strains supported healthy regularity, stool consistency, bowel movement comfort, and ease of bloating.
That’s because these bacteria perform critical functions like the production of SCFAs we mentioned — particularly acetate, propionate, and butyrate — that support wave-like muscle contractions in the intestines in order to facilitate bowel movements.”
Origin: Does the probiotic come from humans or is it derived from soil or animals?
Species and Strain: Lactobacillus acidophilus is different from Lactobacillus rhamnosus, and within each species there can be hundreds or thousands of strains. As we’ll explain later, one could be beneficial for a specific condition and another could be harmful.
Testing: Was the specific strain shown to confer a live microbe-mediated health benefit, as evidenced in clinical studies?
Potency: You’ve probably seen CFU on labels. CFU refers to colony-forming units, which basically tells you how many bacteria in the sample are capable of dividing and forming colonies. A bigger number on the bottle does not always mean better results. The best dose, per strain, is the one that has been studied in humans and shown to deliver positive outcomes.
And CFU has become a marketing tool. Many probiotics today proclaim outrageously enormous CFU counts, but are unable to survive the trip from manufacture to store shelf, much less the journey from your mouth, through your acidic digestive process, to your gut. Oftentimes, to get around this, the number on the box will refer to “time of manufacture,” when really, it should tell you what amount will still remain viable near the expiration date.
More interestingly, a new form of measurement has emerged that you can keep an eye out for: AFU. AFU stands for Active Fluorescent Units. It’s measured with flow cytometry, a process where probiotic cells are tagged with fluorescent “markers” and counted by a laser as they pass through a tube. Through AFU, we are able to calculate a more precise measurement of all viable cells, including ones that are efficacious but not necessarily culturable (and therefore would not be counted in a traditional plated CFU measurement).
Survivability and Viability: The stomach is an inhospitable place: hydrochloric acid, potassium chloride, sodium chloride — mucus, too. You can imagine that this destructive environment presents quite an obstacle course for living microbes in our food or dietary supplements, which need to make their way through the stomach and small intestine alive, in order to carry out their full range of fermentative functions in the colon.
The realities of the human digestive system should be considered in developing probiotics, which is possible using the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®), a model of human digestion that recreates the physiological conditions and biological processes (food uptake, peristalsis, digestive enzymes, pancreatic and bile acids, and time spent in each step) representative of the human gastrointestinal tract. (Our Daily Synbiotic, with its 2-in-1 capsule technology, protects against stomach acid and safeguards the viability of 53.6 billion probiotic bacteria through digestion, delivering 100% of the starting dose of the live bacteria to the end of the small intestines and into the colon.)
What is the best time to take a probiotic?
Now that you know what to consider when choosing a probiotic, when should you take it? The time of day is less important than understanding that you ideally want to take a probiotic on an empty stomach (and at least 15-45 minutes before a meal, or 2-3 hours after eating). For most people that means first thing in the morning or right before bed. Why take it on an empty stomach? As we suggested in the “survivability and viability” consideration above, stomach acid is potentially harmful to living microbes, and as you might expect, having food in your stomach means more stomach acid and bile is released, making it a more challenging environment to pass through. However, we also acknowledge that each person is unique, and what’s ideal for probiotic survival may not be ideal for your needs. You know your body best—we recommend trying to find a time to take your probiotic that works best for your particular ecosystem. Consistent, daily intake is the most important thing.
How long does it take for probiotics to work?
Let’s refer back to the section in which we discussed how probiotics work and remember that different strains have been clinically studied for different benefits, so the answer will be different for each strain and its particular dosage. In the 300-person study on Lactobacillus plantarum SD-LP1-IT and Bifidobacterium breve SD-BR3-IT, participants experienced significant benefits to their digestive health within 15 days. Those are fast-acting microbes.
What are the signs probiotics are working?
Again, this will depend on the strain and its associated benefits. For participants in the 300-person study on Lactobacillus plantarum SD-LP1-IT and Bifidobacterium breve SD-BR3-IT, the signs were pretty clear. This combination of strains supported healthy regularity, stool consistency, bowel movement comfort, and ease of bloating.
Who invented probiotics?
Nobel Prize-winning embryologist Élie Metchnikoff is generally regarded as having started the modern scientific field of probiotics. In the 1910s through the 1930s, gastrointestinal issues were treated with Lactobacillus acidophilus based on the work of Metchnikoff and Yale bacteriologist Leo Rettger.11 The term “probiotics” emerged later, between the 1950s and the 1970s, and in the 1980s it was used routinely in medical and veterinary literature to describe live organisms that were introduced to improve the host microbial balance.
This info is all on the website! Xx
I hope you enjoy this product, so much you decide to buy it for yourself and your loved ones!!
Owner and Founder At The Goddess Bibles A Memoir By Laura Zukerman
Becoming Your Inner Goddess/God
Goddess/God on Fire ❤