Brain inspired autonomous driving is a rapidly developing field that seeks to develop autonomous vehicles that can operate more efficiently…
Treatment Strategies for Head and Neck Cancer: Confronting Cancer Through Multidisciplinary Collaboration
Head and neck cancer is a complex disease that requires a multidisciplinary approach for effective treatment. Here are some treatment…
Molecular and Metabolic Regulation on the Interaction with Beneficial Fungi
Plants have evolved complex mechanisms to interact with beneficial fungi, such as mycorrhizal fungi and endophytes, which can provide them…
15 Years of Frontiers in Human Neuroscience: The History of Brain, Computer Interfaces
Frontiers in human neuroscience is a leading open-access journal that has published numerous articles on brain-computer interfaces (BCIs) over the…
Rising Stars in Child Health and Interventions
There are numerous rising stars in child health and interventions, but here are a few examples. 1. Dr. Rhea Boyd:…
Pathophysiology of Diabetic Kidney Disease
Diabetic kidney disease (DKD) is a complication of diabetes mellitus that affects the kidneys. The pathophysiology of DKD is complex…
Pharmacotherapeutics for Bone and Soft Tissue Tumors
Pharmacotherapeutics for bone and soft tissue tumors typically involve the use of chemotherapy, targeted therapy, and immunotherapy. The choice of…
Drug Metabolism Induced Organ Toxicity
Drug metabolism-induced organ toxicity is a type of drug induced toxicity that occurs when a drug or its metabolites cause…
Use of Bioactive’s for Treatment of Respiratory Diseases
Bioactive’s, also known as bioactive compounds, are natural compounds found in plants, animals, and microorganisms that have biological activity and…
the role of PPARs in Tumor Energy Metabolism
PPARs (peroxisome proliferator-activated receptors) are a group of nuclear receptors that play a crucial role in regulating energy metabolism in…
The Monoaminergic Field and its Relevance to Mental Disorder
The monoaminergic system refers to the neurotransmitters dopamine, norepinephrine, and serotonin, which are involved in regulating mood, motivation, and other…
Integrating Genetics and Proteomics for drug discovery
Integrating genetics and proteomics can be a powerful approach for drug discovery. By analyzing genetic variations and protein expression patterns,…
The use of Pluripotent Stem Cells for Disease Modeling and Drug Discovery
Pluripotent stem cells have the potential to differentiate into any cell type in the body, making them a valuable tool…
Therapies for Brain Injury
Brain injury is a complex and often devastating condition that can result from a variety of causes, including trauma, stroke,…
Novel Sources of Natural Active Compounds for Skin Protection and Treatment for Skin Disorders
There are several novel sources of natural active compounds for skin protection and treatment for skin disorders. Some of these…
New Strategies for Reversing Cancer Therapy Resistance
There are several new strategies being explored for reversing cancer therapy resistance, including the following. 1. Combination Therapy : Using…
Herbal Medicine and their Bio-active Metabolites as Potential Anti-Cancer Agents
Herbal medicine has been used for centuries as a source of natural remedies for various ailments, including cancer. Many plants…
The Roles of Immune Cell Homeostasis in Cancer Research and Therapeutic Response Volume II
Immune cell homeostasis plays a crucial role in cancer research and therapeutic response. Volume II of this topic expands on…
Overcoming Immuno-Modulatory Barriers in the delivery of Anticancer Therapeutics
The immune system plays a critical role in regulating the efficacy of anticancer therapeutics. However, it can also act as…
Where we need to go with Precision Medicine
Precision medicine is an emerging approach to healthcare that takes into account individual differences in genetics, environment, and lifestyle to…
Sepsis and How to Cure It
Sepsis usually begins with an infection, which can be caused by bacteria, viruses, fungi, or parasites. The infection can originate…
Glycoscience and Glycotechnology Applied to Gastrointestinal Diseases
Glycoscience and glycotechnology have been applied to gastrointestinal diseases in several ways. Firstly, the study of glycosylation patters of proteins…
The Mechanistic Investigation and Emerging Therapies for Friedreichs Ataxia?
Friedreichs Ataxia (FA) is a rare genetic disorder that affects the nervous system and causes progressive damage to the spinal…
Can we use non-invasive or invasive neurostimulation to treat seizure disorders including both the seizures and the common co-morbidities?
Yes, non-invasive and invasive neuro-stimulation can be used to treat seizure disorders, as well as the common co-morbidities associated with…
Current medical targets effectively treat 60-70% of patients with epilepsy. However, many of the interventions have debilitating side-effects. Can we leverage data related to the mechanisms of epilepsy to develop innovative treatments with high efficacy and low side-effect profiles?
Yes, leveraging data related to the mechanisms of epilepsy can help develop innovative treatments with high efficacy and low side…
Can we leverage new technologies (genomics, gene-encoded sensors, high resolution microscopy, electrophysiology, MRI, etc) spanning the levels of cell culture, animal model and our patient population, to uncover mechanisms or develop innovative therapies?
Yes, new technologies such as genomics, gene-encoded sensors, high-resolution microscopy, electrophysiology, and MRI scans can be leveraged to uncover mechanisms…
Are there specific changes in neurons, astrocytes or microglia that trigger seizures or lead to the development of epilepsy?
Yes, there are specific changes in neurons, astrocytes, and microglia that can trigger seizures or lead to the development of…
Why and how do epileptic networks form? How do seizures propagate across a network of neurons?
Epileptic networks form when there is an abnormal synchronization of neuronal activity in the brain. This synchronization can be caused…
What differences in nervous system processing occur during normal aging that can give rise to age-related hearing deficits, and how can they be minimized or eliminated?
Normal aging is associated with a decline in various aspects of nervous system processing, including changes in neural structure, function…
What are the synaptic mechanisms of adaptive plasticity, i.e. how are particular synapses strengthened or weakened?
Adaptive plasticity refers to the ability of the brain to change and adapt in response to new experiences or changes…
How does the cerebral cortex use attention to allow people to hear and understand sounds in noisy environments?
The cerebral cortex uses attention to allow people to hear and understand sounds in noisy environments by selectively enhancing the…
How do neurons in the cerebral cortex normally function that allows one to process complex sound signals such as speech?
Neurons in the cerebral cortex function by receiving and transmitting electrical and chemical signals. In the case of processing complex…
How does attention affect the way we see things?
Attention plays a crucial role in the way we see things. It helps us focus on important information while filtering…
How do other sensory modalities like hearing become integrated with our visual perception?
The integration of different sensory modalities is known as multi-sensory integration. It occurs at various levels of the brain. One…
How does information from the retina get processed in visual cortex?
The information from the retina is carried to the visual cortex through the optic nerve. The visual cortex is located…
What causes age-related macular degeneration?
Age related macular degeneration (AMD) is a complex disease that is caused by a combination of genetic and environmental factors.…
Why do retinal ganglion cells die in glaucoma?
Retinal ganglion cells (RGCs) die in glaucoma due to a combination of factors, including elevated intraocular pressure (IOP), oxidative stress,…
How does retinal degeneration activate the immune system, and how does controlling the immune system affect degeneration?
Retinal degeneration can activate the immune system in several ways. One way is through the release of damage-associated molecular patterns…
How do retinal circuits perform their computations?
Retinal circuits perform their computations through a complex network of cells and synapses that process visual information. The retina contains…
How do rod and cone photoreceptors signal light in dim and bright light?
Rod photoreceptors are specialized cells in the retina that are responsible for detecting light in low-light conditions. In dim light,…
How much what plasticity remains in the tissue surrounding the injury, or in the uninjured portions of the brain? Are there ways to enhance plasticity?
There is no evidence to suggest that the brain has a remarkable capacity for plasticity, even in the tissue surrounding…
Can we use our findings related to mechanism of injury to develop novel and targeted interventions to improve outcome following TBI or stroke?
Yes, understanding the mechanisms of injury can help researchers develop novel and targeted interventions to improve outcomes following traumatic brain…
How can we apply novel and innovative technologies (genomics, gene-encoded sensors, advanced microscopy, neuro-modulation, PET, MRI, etc.) to better characterize the effects of injury on long-term brain anatomy and function?
There are several ways in which novel and innovative technologies can be applied to better characterize the effects of injury…
Are there biomarkers (i.e., blood, tissue, EEG) that can help predict the severity of the initial injury or the potential for recovery of function?
Yes, there are several biomarkers that can be used to predict the severity of initial injury and potential for recovery…
What are the primary causes and consequences of cell death following injury?
There are several primary causes of cell death following injury, including the following. 1. Necrosis: This is a form of…
What are some of the major cellular and molecular pathways involved in the long-term pathology related to chronic disability in TBI and stroke?
There are several cellular and molecular pathways involved in long term pathology related to chronic disability in traumatic brain injury…
How the brain forms predictive models of the environment
The brain is constantly processing and interpreting sensory information from the environment to create a predictive model. This predictive model…
The relationship between neural activity and reward-based behavior
Neural activity and reward based behavior are closely related. When we experience something rewarding or pleasurable, such as eating our…
How attention and decision-related signals alter neural representations of sensory stimuli
Attention and decision related signals can alter the neural representations of sensory stimuli in several ways. Attention can modulate how…
Links between attention, emotion, and anxiety
Attention, emotion and anxiety are interrelated in several ways. Firstly, attention is a cognitive process that involves focusing on specific…
Becoming The Goddess You Were Meant To Be 
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